GenuineSelect-TOX

GenuineSelect-TOX

Clinical trial-in-a-Dish platform for
Drug-Induced Liver Injury

GenuineSelect-TOX is a DILI prediction platform that uses donor-dependent reprogrammed spheroids to assess chemical-mediated toxicity in a population view

Accurate prediction of clinical DILI

Study performed on 109 healthy donors randomly distributed into 5 independent cohorts of 24 individuals
Age: 40.8 ±11.5
Males: 44
Females: 65

DILI effect based on host risk factors

Data from 109 donors included in the study with 7 DILI positive drugs