Clinical trial-in-a-Dish platform for Drug-Induced Liver Injury
GenuineSelect-TOX is a DILI prediction platform that uses donor-dependent reprogrammed spheroids to assess chemical-mediated toxicity in a population view
Accurate prediction of clinical DILI
Study performed on 109 healthy donors randomly distributed into 5 independent cohorts of 24 individuals
Age: 40.8 ±11.5
Males: 44
Females: 65
DILI effect based on host risk factors
Data from 109 donorsincluded in the study with 7 DILI positive drugs